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Name | : | Dr Mahesh Kumar Sah |
Designation | : | Assistant Professor |
Department | : | Bio-Technology |
Qualification | : |
Ph.D (Integ.) Biotechnology and Medical Engineering (NIT Rourkela) B.Tech Biotechnology (Bundelkhand University, Jhansi) |
Address | : |
Department of Biotechnology Dr B R Ambedkar National Institute of Technology, Jalandhar (Punjab) - 144011 |
Phone | : | +91-7095044510 |
Email ID | : | sahmk@nitj.ac.in |
Fax | : |
Personal Web Link | : | |
Google Scholar Link | : |
Dr. Mahesh Kumar Sah |
Research Interests | : | Biomaterials for Tissue Engineering, Stem Cell Research, Nanotechnology, Biopolymers for Environmental Engineering |
Brief Research Profile: | : | My research area, Tissue engineering, allows the repair or regeneration of cells, tissues, and organs which have lost their function due to disease, injury or congenital defects. This engineering approach in medicine offers remedy to existing problems through delivery of stem cells and bioactive molecules onto three dimensional (3D) artificial extracellular matrix (bio-scaffold) prepared from either natural or chemically synthesized biocompatible and biodegradable materials (biomaterials). It may be either metallic, polymeric, ceramic, or composite. The wide range of natural polymer and ceramic resources still to be unveiled as biomaterial for tissue engineering applications. My research area deals with the processing and modification of silk fibroin from Bombyx mori, double layered eggshell membrane, hair keratine, eggshell, crab shell, and adding more to the list for the development of bioscaffold. The fabrication of 3D scaffolds with macro/micro porous architecture with nanoscale biopolymers and bioceramics by solvent casting-particulate leaching and freeze-drying methods have been employed in my research, however, efforts are being made towards electrospinning and 3D organ printing. The developed promising bioscaffolds have been further studied with mesenchymal stem cells (stem cell research) derived from peripheral and umbilical cord blood for bone and cartilage tissue regeneration. The influence of introducing bioactive molecules (metal ions, molecules, nanomaterials) on the induction of stem cell proliferation and osteogenesis is key objective of my research. The nanotechnology is contributing remarkably towards my research for the development of biomaterials with nanoscale topography or fibres to induce the cell proliferation in a particular fashion and directs towards cell differentiation of interest. Many of these natural polymers and ceramic biomaterials also exhibit the affinity towards heavy metal ions and thus processed and modified eggshell membrane and hair keratin is deciphered for water treatment (environmental engineering). The treatment of polluted drinking water and wastewater from industries could be well treated for the removal of heavy metals with developed biopolymeric system. Efforts are being made to fabricate such filters in an economic, reusable, and readily available form for wide applications without any side effect on human and environmental well-being. |
Year | Conference | Publication |
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2019 | International Conference on Biomedical Engineering, Bioscience, Bioinformatics, Biochemistry Cancer Biology, Molecular Biology and Applied Biotechnology (BCM-2019), 12 January 2019, Krishi Sanskriti, Jawaharlal Nehru University, New Delhi, India | M. K. Sah, Partially De-Proteinized Human Hair: A Novel BioMaterial for Arsenic Remediation |
2019 | International Conference on Advanced Materials (ICAM-2019), 6-7 March 2019, Centre of Nanoscience and Nanotechnology, Jamia Milia Islamia, New Delhi, India | M. K. Sah, M. Badhan, R. Mane, B. B. Panigrahi, S. N. Rath, Calcified chitosan biopolymer matrix from crab shell supporting the proliferation of human umbilical cord blood derived mesenchymal stem cells |
2019 | International Conference on Materials and Manufacturing Methods (MMM-2019), 5-7th July, 2019, National Institute of Technology, Tiruchirappalli, India | N.A.L. Breikia, B.A. Albadria, S. Alsheriqi, B. Alshabibia, S. Al-Mammarib, S. Premkumar, M. K. Sah, M.S.Sudhakar Characterization of Catla catla and Oreochromis niloticus Fish Scales Derived Hydroxyapatite Scaffolds for Regenerative Medicine |
2019 | 2nd International Conference on Emerging Trends in Traditional and Technical Textiles (ICETT-2019), 1-3rd November, 2019, Department of Textile Technology, Dr. B. R. Ambedkar National Institute of Technology, Jalandhar, Punjab | A. Aggarwal, M. K. Sah, Soluble eggshell membrane protein/PVA blend three-dimensional porous sponge as artificial skin model |
2019 | 2nd International Conference on Application of Biotechnology in Industry and Society (ABIS-2019), November, 2019, Department of Biotechnology, Dr. B. R. Ambedkar National Institute of Technology, Jalandhar, Punjab | A. Aggarwal, M. K. Sah, Tunable collagen hydrogel patches as artificial skin |
2019 | XXXVIII Annual Conference of Indian Council of Chemists (ICC), 26-28th December 2019, Jaipur National University, Jaipur, Rajasthan, India | M. K. Sah, The physical chemistry of biomolecules: new paradigm of studies relevant to life phenomena |
2017 | Tissue Engineering and regenerative medicine international society (TERMIS) European Chapter Meeting, 6 - 30 June, 2017, Davos, Switzerland | Uday K. Rooprath, M. K. Sah, S. N. Rath, A novel approach for the synthesis and fabrication of naturally derived biocompatible β-TCP scaffolds through mechanical stimulation |
2016 | India International Science Festival (IISF) Young Scientists’ Conclave (YSC), Govt. of India, 8-11 December, 2016, New Delhi, India | M. K. Sah, Uday K. Rooprath, Bharat B. Panigrahi, S. N. Rath, Effect of pretreatment on Ultrasonic Assisted Extraction of Water Soluble Eggshell Membrane Protein |
2016 | World Biomaterial Congress-2016 (WBC2016), 23-27 May, 2016, Montreal, Canada | M. K. Sah, S. N. Rath, I. Banerjee, K. Pramanik, SEP cross-linked porous Silk Fibroin/PVA scaffolds for tissue regeneration: Fabrication, Characterization and Cyto-compatibility studies |
2011 | National conference on Tissue Engineering: Prospects & Challenges (TEPC-2011),21-22 January , 2011, NIT Rourkela, India | M. K. Sah, K. Pramanik, Development, Characterization and Cyto-compatibility of Silk Fibroin/PVA scaffolds for bone tissue engineering |
2010 | International Conference on Biomaterials, Artificial Organs & Tissue Engineering (ICBAT 2010), 28th February to 1st March, 2010, SCMS Cochin, India | M. K. Sah, K. Pramanik, Biorelevant study of Silk Fibroin nHAP composite scaffolds for bone tissue engineering |
2010 | International conference on Biomedical Engineering and Assistive Technologies (BEATS-2010), 17-19 December, 2010, NIT Jalandhar, India | M. K. Sah, J. Sadanand, A. Kumar, Development and Biorelevant study of Salt Leached Polyvinyl Alcohol (PVA) Scaffolds |
2009 | National Conference on Biotechnology for Human Development (SBTI-2009), School of Biosciences Technology, 27-28 November , 2009, VIT University, India | M. K. Sah, A. Kumar, K. Pramanik, Use of Experimental Design Method to Investigate the extraction of Fibroin Protein from Bombyx mori Silk Cocoon |
2009 | World Conference on Regenerative Medicine (WRM-2009), 29-31 October, 2009, Leipzig, Germany | K. Pramanik, M. K. Sah, Preparation and Characterization of Porous Silk Fibroin Scaffolds using Salt Leaching Method for Tissue Engineering Applications |
2008 | International Conference on Medical Materials, devices & Regenerative Medicine (MMDRM-2008), organized by SBAOI & STERMI, College of Biomedical Engg. & Applied Sciences, November 23 -25, 2008, Kathmandu, Nepal | M. K. Sah, K. Pramanik, Surface Modification and Analysis of Natural Polymers for Orthopaedic Tissue Engineering |
Type | Title | Publisher | Authors | ISBN/ISSN No. | Year |
---|---|---|---|---|---|
Book Chapter | "Engineering biomaterials for the bioremediation: Advances in nano-technological approaches for heavy metals removal from natural resources”, In Maulin Shah, Susana Rodriguez Couto, Sevinc Sengor (Eds.), Emerging Technologies in Environmental Bioremediation | ELSEVIER | MS Sudhakar, A Aggarwal, MK Sah | 978-0-12-819860-5 | 2020 |
Book Chapter | "Biological Approaches for Intoxification of Aquatic System”, In: Advances in Environmental Engineering | Excel India Publishers, New Delhi | M. K. Sah, R. Kaur, C. Bhattacharya, & K. Pramanik | 978-93-80043-45-6 | 2009 |
Role | Project Type | Title | Funding Agency | From | To | Amount | Status | Co-Investigator |
---|---|---|---|---|---|---|---|---|
Principle Investigator | Seed Grant | Development of human hair keratin based matrix for arsenic removal from water resources | TEQIP Phase-III | 03-12-18 | 02-12-19 | 2,00,000 | Ongoing | Dr. Indu Chauhan |
Category | Type | Title | Venue | From | To | Designation |
---|---|---|---|---|---|---|
Expert Talk | National | Talk by "Nalin Singh-Life Coach, Business Strategy consultant, Author & Entrepreneur” | NIT Andhra Pradesh, Tadepalligudem (A.P.) | 24-03-2017 | 24-03-2017 | Organizing Member |
Workshop | National | TEQIP Workshop on Tissue Engineering: Biomaterials and stem cells for manufacturing of biological tissues | Indian Institute of Technology Hyderabad | 20-03-2017 | 25-03-2017 | Invited Instructor |
Workshop | National | TEQIP Workshop on Biomaterials and stem cells for manufacturing of biological tissues | Indian Institute of Technology Hyderabad | 18-07-2016 | 23-07-2016 | Instructor |
Seminar | National | Biomedical Instrumentation & Scope (BIS-2013) | Mahavir Institute of Engineering & Technology, Bhubaneswar, Odisha | 13-09-2013 | 14-09-2013 | Convener |
FDP/STC | National | Recent Advancement in Biomaterials and Nanotechnology for Biomedical Applications | Dept. of Biotechnology, Dr. B. R. Ambedkar National Institute of Technology Jalandhar, Punjab | 24-05-2019 | 28-05-2019 | Course Coordinator |
Expert talk | National | Patent, Design, and Trademark | Department of Biotechnology, Dr B R Ambedkar National Institute of Technology Jalandhar, Punjab | 24-01-2020 | 24-01-2020 | Convener |
Expert talk | National | Ionic liquids as green solvent for processing and chemical modification of Biomaterials | Department of Biotechnology, Dr B R Ambedkar National Institute of Technology Jalandhar, Punjab | 18-02-2020 | 18-02-2020 | Convener |
Webinar | National | Innovations against COVID-19: Start-up opportunities for medical informatics, biopharma, and biomedical products | Department of Biotechnology, Dr B R Ambedkar National Institute of Technology Jalandhar, Punjab | 27-06-2020 | 27-06-2020 | Convener |
Designation | Organization |
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Founder Life Member | Indian Society of Nanomedicine, ISNM-LF-110, New Delhi since December 2017 |
Life Member | Society for Biomaterials and Artificial Organs (India), SBAOI, LM518, since November 2007 |
Reviewer | Materials Science and Engineering: C, Elsevier, ISSN: 0928-4931, since 2015 |
Reviewer | Journal of Applied Polymer Science, John Wiley & Sons Inc., Online ISSN: 1097-4628 since 2012 |
Reviewer | eXPRESS Polymer Letters, ISSN 1788-618X, Budepest University of Technology and Economics since 2013 |
Reviewer | Environmental Engineering Science, Mary Ann Libert Inc., ISSN:1092-8758 since 2016 |
Life Member | Asian Polymer Association (APA), LM-542, since March 2019 |
Scholar Name | Research Topic | Status | Year | Co-Supervisor |
---|---|---|---|---|
Ms. Aakriti Aggarwal | Valorization of agro-waste materials and its applications in tissue engineering | Ongoing | 2019 | -- |
Student Name | Dissertation Title | Status | Year | Co-Supervisor |
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Name | Reg./Ref. No. | Date of Award/Filling | Organization | Status |
---|---|---|---|---|
Mahesh K. Sah, Uday K. Roopavath, Subha N. Rath, Bharat B. Panigrahi, METHOD FOR EXTRACTION OF WATER SOLUBLE EGGSHELL MEMBRANE PROTEIN | 201731017393 | 23-11-2018 | Intellectual Property India (GOI) | Published |
Mahesh Kumar Sah, SINGLE PIECE FULL BODY PPE COVER | 329225-001 | 08-05-2020 | Intellectual Property India (GOI) | Filed |
Position Held | Organization | From | To |
---|---|---|---|
Faculty-in-charge, Innovation & Entrepreneurship Club | NIT Andhra Pradesh, Tadepalligudem (A.P.) | 29-08-2017 | 06-01-2018 |
Faculty Adviser, Training and Placement | Dept. of Biotechnology, NIT Andhra Pradesh, Tadepalligudem (A.P.) | 10-2017 | 06-01-2018 |
Faculty Adviser, Biotechnology Association (BA) | Dept. of Biotechnology, NIT Andhra Pradesh, Tadepalligudm (A.P.) | 22-11-2016 | 31-05-2017 |
Technical Head, Dept. of Biotechnology | Cultural and Technical Fest, VULCANZY-2K17, NIT Andhra Pradesh | 24-03-2017 | 25-03-2017 |
Member, Institutional R&D Committee | MIET, Bhubaneswar, Odisha | 07-2013 | 12-2014 |
Member, Flying Squad Team for Regular Examination in Affiliated Institutions | Biju Patnaik University of Technology (BPUT), Odisha | 04-2014 | 12-2014 |
Title | Activity | Given by | Year |
---|---|---|---|
Media Coverage | Developed “SINGLE PIECE FULLBODY PPE COVER" for COVID-19 | Coverage by 10-05-2020: Hindustan, Deoghar, Jharkhand edition; 12-05-2020: Prabhat Khabar, Deoghar, Jharkhand edition; 01-06-2020: Dainik Jagran, Jalandhar, Punjab Edition | 2020 |
Green ThinkerZ Preeminent Engineer Award-2019 | Contribution to the field of biomaterials and tissue engineering | Green ThinkerZ - India in association with Centre for Modern Construction, Western Sydney University, Australia | 2019 |
Media Coverage | Research work on "Mechanochemically synthesized phase stable and biocompatible β-tricalcium phosphate from avian eggshell for the development of tissue ingrowth system" in collaboration with IIT Hyderabad, India | NDTV India, The Hindu, IndiaToday, Economictimes, OdishaTV, ANI News, Dainik Bhaskar, Telugu News and many more during 15-17th August 2019 | 2019 |
Bharat Vikas Award -2017 | Contribution to the field of tissue engineering | Institute of Self Reliance India (ISR India), Bhubaneswar, India, 19th November, 2017 | 2017 |
Developing Country Sponsorship Award-selected | Presentation in World Biomaterial Congress-2016 (WBC2016), 17-22 May, 2016, Canada | AccelLAB Inc., Quebec, Canada | 2016 |
DBT-Research Associate (RA) Fellowship | Research at Dept. of Biomedical Engg., IIT Hyderabad | Dept. of Biotechnology (DBT), Govt. of India | 2015-2016 |
First Prize | National Level Essay Competition on "Bioremediation of Aquatic System" | Institute of Environmental & Developmental Studies, Bundelkhand University, Jhansi | 2006 |
Third Prize for Rotary Cell Culture System Model | All India Engineering Projects Contest "Techtrix 2005" | Bundelkhand University, Jhansi | 2005 |